An intensive therapy regimen involving medication, diet and behavioral changes successfully reversed Alzheimer’s-related memory loss in a new trial, according to research from the University of California, Los Angeles. The findings were published in the journal Aging.
The study involved 10 people experiencing memory loss from Alzheimer’s and other conditions. Of these, nine showed memory improvement within 3-6 months of starting the program. The one patient who did not improve had late-stage Alzheimer’s.
The improvements also have been lasting, with the longest duration being 2.5 years, according to study author Dale Bredesen, M.D., of the Mary S. Easton Center for Alzheimer’s Research at UCLA and the Buck Institute. In one case, a participant eliminated gluten and simple carbohydrates, began yoga and meditation, went on hormone replacement therapy and daily vitamins, and began a regular exercise routine.
The multi-pronged approach is meant to address various changes wrought by Alzheimer’s; drugs have failed because they attack a single aspect of the disease, which involves an extensive network of molecular interactions.